Myocardial regeneration is restricted to early postnatal life, when mammalian cardiomyocytes still retain the ability to proliferate. The molecular cues that induce cell cycle arrest of neonatal cardiomyocytes towards terminally differentiated adult heart muscle cells remain obscure. In this 2021 paper it is reported that the miR-106b∼25 cluster is higher expressed in the early postnatal myocardium and decreases in expression towards adulthood, especially under conditions of overload, and orchestrates the transition of cardiomyocyte hyperplasia towards cell cycle arrest and hypertrophy by virtue of its targetome.

All abstracts of previous Heart Failure Association Winter Research Meeting (January 2021) are now published in the European Journal of Heart Failure: https://doi.org/10.1002/ejhf.2100

The European Society of Cardiology and Harteraad, both partners in the TRAIN-HEART network, focus on the close involvement of patients in cardiovascular research.

Presenter: Professor Mauro Giacca

Title: High throughput screening

In this paper, the group of Prof. Mayr at King’s College London assessed RNAemia, antibody response against SARS-CoV-2 and proteomic profiles in serial blood samples from COVID-19 patients admitted to two Intensive Care Units.

Review paper: Non-Coding RNA Databases in Cardiovascular Research.

Authors: Deepak Balamurali and  Monika Stoll (Maastricht University).

This 2021 conference is set to explore the latest developments in RNA delivery agents and RNA-based therapeutics with the latest case studies on advanced mRNA technologies, oligonucleotide delivery, therapeutic applications and future trends and innovations.

Saturday, 15 May - Tuesday, 18 May 2021

Heart Failure is the world's leading congress for experts in cardiology to discuss strategies for a universal approach towards the prevention and treatment of heart failure.

Since 2000, on the last Sunday in September we celebrate World Heart Day in order to raise global awareness of the importance of cardiovascular diseases and promote their control. The event arose as an initiative of the World Heart Federation and enjoys the patronage of the World Health Organization (WHO) and the United Nations Educational, Scientific, and Cultural Organization (UNESCO).

Pandemic 101: lessons from COVID-19 to young researchers

Nice workshop of Prof. Manuel Mayr, invited by the Alan Turing Institute on "Making the most of 'omics data"

The second edition of the X-omics festival “the future is now!” will take place online, on Monday September 28th 2020 from 09.30 – 14.00 CEST.

Bringing stakeholders together to shape future research and innovation policy.

ESC Congress – the world’s largest cardiovascular event – moves 100% online for the first time in its 70-year history, to create ESC Congress 2020 – Challenging Times, Infinite Possibilities. The ESC Congress Programme Committee has assembled the very latest cardiovascular research across over 500 sessions with 750 experts from 49 countries.

The TRAIN-HEART MSCA ITN is now also on Twitter! You can get all your updates about the ongoing research in this consortium, meet the researchers and more! Make sure you follow @TRAINHEART4 on Twitter!

The TRAIN-HEART ESR journal club is launched this week and will meet regularly online to critically evaluate recent articles in the academic literature, such as the scientific literature, medical literature, or philosophy literature.

On Monday 16 March 2020, the Heart Failure Association (HFA) organized a dedicated webinar: "Next generation RNA therapeutics. Background and clinical development in cardiovascular disease".

As part of their outreach skills training, the scientist have created three educative video tutorials.

From 20 to 24 January 2020 the first TRAIN-HEART network meeting and training event was organized at the Technical University Munchen (Germany).

Re-advertisement of 4 positions. Are you interested? Check Project 2, Project 5, Project 14 and Project 15 on Euraxess or the TRAIN-HEART website.